Inflammatory Conditions I

Acute and Chronic Prostatic Inflammation:

• Diagnosed clinically and treated by antibiotics.
• Acute prostatitis ; - sheets of neutrophils within the acini  -intraductal desquamated cellular debris - stromal edema ad hyperemia
• The biopsy of TUR of a man with clinical acute prostatitis is contraindicated, can result in sepsis or other complications such as stricture.
• Should be diagnosed as "prostate tissue with acute inflammation"
• Prostatic abscesses ; bladder outlet obstruction secondary to a lower urinary tract infection, usually due to coliform organisms. Much less frequently dissemination from skin -stafilococcus or complication of biopsy or instrumentation.
• Chronic inflammation (in BPH) and chronic prostatitis distinguish is difficult
• Prostatitis may lead to serum PSA elevation.
• We comment on the histologic presence of chronic inflamation only when its prominent.

Malokoplakia: 

• As in bladder majority of man prostatic malokoplakia have urinary infection , most frequently with E.coli.
• In USG  prostatic induration and hipoechoic lesion.
• Michaelis Gutmann bodies 

*Source: Biopsy Interpretation of the Prostate -Jonathan I. Epstein