Inflammatory Conditions II

Granulomatous Prostatitis:
*infectious granulomas
*nonspesific granulomatous prostatitis
*postbiopsy resection granulomas
*systemic granulomatous prostatitis

Mycotic Prostatitis:

• Immuncompromised hosts 
• Blastomycosis, coccidiomycosis, cryptococcosis (most common)

Mycobacterial Prostatitis:

• Can be seen in systemic tbc but nowadays its commonly seen in as a complication of BCG immunotherapy for superficialbladder carcionoma.
• Hitologically the findings in BCG prostatitis are indistinguishable from those of tbc prostatitis occuring as a result of systemic infection.

Nonspesific Granulomatous Prostatitis:

• In 25387 benign specimens of the %5
• In the etiologyof this lession is thought to be rxn to bacterial toxins, cell debris, and secretions spilling into the stroma fro blocked ducts.
• Mimics prostate carcinoma on rectal examination and USG.
• Earliest lesions; dilated ducts and acini filled with neutrophils, debris, foamy histiocytes and desquamated epithelial cells. Rupture of these ducts and acini results in a localized gralunomatous and chronic inflammatory rxn. Older lesions of nonspesific granulomatous prostatitis show a more prominent fibrous component.
• Treated with warm sitz baths, fluids and antibiotics.
• Although small abscesses may be present at the center of nodules of nonspesific granulomatous prostatitis, caseous necrosis is absent.

*Source: Biopsy Interpretation of the Prostate -Jonathan I. Epstein